Characterization and Biodegradation Studies for Interpenetrating Polymeric Network (IPN) of Chitosan-Amino Acid Beads
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چکیده
منابع مشابه
Characterization and Biodegradation Studies for Interpenetrating Polymeric Network (IPN) of Chitosan-Amino Acid Beads
The paper describes the synthesis of pH sensitive interpenetrating polymeric network (IPN) beads composed of chitosan, glycine, glutamic acid, cross linked with glutaraldehyde and their use for controlled drug release. The drug was loaded into beads by varying their composition such as, amount of crosslinker glutaraldehyde, ratio of chitosan, glycine and glutamic acid. The beads were characteri...
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The aim of this present study was to develop a pH sensitive interpenetrating polymeric network (IPN) hydro gels (HG) based on chitosan-acryl amide-grafted-poly ethylene glycol (CTS-AM-PEG) followed by hydrolysis that are cross-linked with glutaraldehyde (GA). Cefotaxime is an antibiotic drug was successfully loaded in these IPNHG’s. The HGs formed were characterized by Fourier transform infrare...
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Interpenetrating polymer network (IPN) refers to a type of elastomer in which two chemically distinct networks coexist, ideally having a structure that is homogeneous down to the segmental level [1]. The two components are present as co-continuous, interlocking networks (catenanes). This co-continuity can be achieved by kinetic retention of an initially miscible mixture of the monomers used to ...
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Chitosan obtained by alkaline deacetylation of chitin is a non-toxic, biocompatible, and biodegradable natural polymer. Chitosan-based hydrogel polymeric beads have been extensively studied as microor nano-particulate carriers in the pharmaceutical and medical fields, where they have shown promise for drug delivery as a result of their controlled and sustained release properties, as well as bio...
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ژورنال
عنوان ژورنال: Journal of Biomaterials and Nanobiotechnology
سال: 2011
ISSN: 2158-7027,2158-7043
DOI: 10.4236/jbnb.2011.21010